Ken Hsu

The Hsu Laboratory focuses on the discovery of bioactive molecules. A central theme of our group is the development of covalent probes and inhibitors for investigating protein and lipid activity. Our research is multidisciplinary and uses a combination of organic synthesis, bioanalytical chemistry, and bioorganic chemistry. Current efforts include identifying new reactive chemistry, quantifying ligandability of proteins on a proteomic scale, and deciphering structure and function of membrane signals in living systems. Ultimately, we aim to develop new molecules to enable chemical biology and therapeutic discovery.